Protein Biochemistry Group

The Protein Biochemistry Group carries out research, formerly under the direction of Prof. Mike Dunn, into alterations in protein expression in heart disease and in response to cardiac transplantation.

The group has published several papers in this field.

The group was responsible for the establishment and maintenance of the HSC-2DPAGE 2-DE Protein Databases.
The group also maintains a list of other useful sites on the WWW.

Staff (in Nov 2000):

Dr Mike Dunn
Ms Helen Brittan (Helen.Brittan@harefield.nthames.nhs.uk)
Dr Najma Latif (Najma.Latif@harefield.nthames.nhs.uk)
Dr Kit-Yi Leung (Kit-Yi.Leung@harefield.nthames.nhs.uk)
Ms Vaksha Patel (Vaksha.Patel@harefield.nthames.nhs.uk)
Mrs Chris Trand (Chris.Trand@harefield.nthames.nhs.uk)
Dr John Weekes (John.Weekes@harefield.nthames.nhs.uk)
Mr Jules Westbrook (Jules.Westbrook@harefield.nthames.nhs.uk)

Memories of visitors to the laboratory

Major projects include:

Alterations in protein expression in heart disease
Alterations in calcium handling in the development and regression of cardiac hypertrophy
Anti-heart antibodies in cardiac transplantation and heart disease Anti-endothelial antibodies and transplant associated coronary artery disease
Histological and biochemical characterisation of skeletal muscle used for cardiac assistance
Studies of gene expression in the diseased and transplanted heart
Association of polymorphisms in genes encoding the proteins of the renin-angiotensin system with cardiovascular disease

Last modified 23 Oct 2003.
Comments emailed to andrew.dowsey@imperial.ac.uk welcomed.